Selected publications
Selected publications
Legraverend C. and Jay P.: Hierarchy and plasticity in the crypt : back to the drawing board.
Cell Research, vol.21(12) : 1652-1654 (2011). Link
Ecobar M., Nicolas P., Sangar F., Laurent-Chabalier S., Clair P., Joubert D., Jay P. and Legraverend C. : Intestinal epithelial stem cells do not protect a copy of their genome by asymmetric chromosome segregation.
Nature Communications, 2 : 258 (2011). Link
Gerbe F., van Es J. H., Makrini L., Brulin B., Mellitzer G., Robine S., Romagnolo B., Shroyer N. F., Bourgaux J.-F., Pignodel C., Clevers H. and Jay P. : Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.
The Journal of Cell Biology, vol. 192(5) : 767-780 (2011). Link
See the Editorial comment on this article in the same issue of JCB, page 706. Link
Legraverend C., Escobar M. and Jay P. : « The immortal DNA strand » : difficult to digest ?
Cell Stem Cell, vol. 6(4) : 298-299 (2010). Link
Gerbe F., Brulin B., Makrini L., Legraverend C. and Jay P. : DCAMKL-1 expression identifies tuft cells rather than stem cells in the adult mouse intestinal epithelium.
Gastroenterology, vol. 137(6) : 2179-2180 (2009). Link
Dupasquier S., Bastide P., Abdel-Samad R., Jay P., Joubert D., Blache P. and Quittau-Prevostel C. : A new mechanism of SOX9 action to regulate PKC-alpha expression in the intestine epithelium.
Journal of Cell Science, vol. 122(13) : 2191-2196 (2009). Link
Diouf B., Collazos A., Labesse G., Macari F., Choquet A., Clair P., Gauthier-Rouviére C., Guérineau N.C., Jay P., Hollande F., Joubert D. : A 20 amino acid module of PKCvarepsilon involved in translocation and selective targeting at cell-cell contacts.
Journal of Biochemical Chemistry, vol. 284(28) : 18808-18815 (2009). Link
Joubert D., Hollande F., Jay P. and Legraverend C. : Intestinal stem cells : thirty years of a long and exemplary story.
Médecine Science, vol. 25 (5) : 441-444 (2009). Link
Zalzali H., Naudin C., Bastide P. Quittau-Prévostel C., Yaghi C., Poulat F., Jay P. and Blache P. : CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium.
Oncogene, vol. 27 (56) : 7131-7138 (2008). Link
Darido C., Buchert M., Bastide P., Mantamadiotis T., Jay P., Blache P., Joubert D. and Hollande F. : Defective regulation of Claudin-7 by the TCF4/SOX9 pathway promotes loss of polarization of colorectal tumor cells.
Cancer Research, vol. 68 (11) : 4258-68 (2008). Link
Fernandez M.-I., Regnault B., Mulet C., Tanguy M., Jay P., Sansonetti P. J., Pédron T. : Maturation of Paneth cells induces the refractory state of newborn mice to Shighella infection.
The Journal of Immunology, vol. 180 : 4924-4930 (2008). Link
Pannequin J., Delaunay N., Buchert M., Surrel F., Bourgaux, J.-F., Boireau S., Coelho J., Pélegrin A., Baldwin G. S., Shulkes A., Singh P., Pignodel C., , Jay P., Joubert D. and Hollande F. : Beta-Catenin/Tcf4 inhibition after Progastrin-targeting reduces growth and drives differentiation of intestinal tumors.
Gastroenterology, vol. 133 (5) : 1554-68 (2007). Link
Bastide P., Darido C., Pannequin J., Kist R., Robine S., Marty-Double C., Bibeau F., Scherer G., Joubert D., Hollande F., Blache P. and Jay P. : Sox9 regulates cell proliferation ans is required for Paneth cell differentiation in the intestinal epithelium.
The Journal of Cell Biology, vol. 178 (4) : 635-648 (2007). Link
van Es J.H., Jay P., Gregorieff A., Jonkheer S., Taketo M.M. and Clevers H. : Wnt signaling induces maturation of Paneth cells in intestinal crypts.
Nature Cell Biology, vol. 7(4) : 381-386 (2005). Link
Jay P., Berta P. and Blache P. : Expression of the carcinoembryonic antigen gene is inhibited by SOX9 in human colon carcinoma cells.
Cancer Research, vol. 65(6) : 2193-2198 (2005). Link
Blache P., van de Wetering M., Duluc I., Domon-Dell C., Berta P., Freund J.-N., Clevers H. and Jay P. : SOX9 is an intestine crypt transcription factor, Is Regulated by the Wnt pathway and represses the CDX-2 and MUC-2 genes.
The Journal of Cell Biology, vol. 166 (1) : 37-47 (2004). Link